Page generated on Fri Oct 15 12:01:38 2010

dme-mir-957



dme-mir-957

View dme-mir-957 on miRBase

miRNA	Length	Perfect(sense)	Perfect(antisense)	5' moR	5'arm	Loop	3'arm	3' moR	Other	Loop Size	Mature	Star
dme-mir-957	145	99097	3	2	312	12	98769	3	2	23	98769	312

AAGAATATATTATATCCGTAGTGTTGTCCACAATAGACCTTAGTTTTCGACGTGTTTTGGTGTGCTGGGGAGTTCTATTCCGATTGAAACCGTCCAAAACTGAGGCCAACTGTGAGGCGCGAGCATCTATCCAAAAAGCGATACC
.........................(((((((...(.((((((((((.((((.((((..((......((((......)))).))..)))))))).)))))))))).)...)))).)))...........................-33.30
....................(((((((.((((...(.((((((((((.((((.((((..((......((((......)))).))..)))))))).)))))))))).)...))))..((....)).............))))))).-39.70
Sense strand

	Size	Blast	Total	SRR031696_2152	SRR001345 ago2 non-beta-eliminated	V090 CS  male total RNA	SRR031703 Total small RNAs from r2d2 homozygous flies	SRR029633 total small RNAs from hen1 homozygous flies	SRR031699 Total small RNAs from dcr-2 homozygous flies	SRR031701 Total small RNAs from r2d2 heterozygous flies	SRR031697 Total small RNAs from dcr-2 heterozygous flies	SRR031692 Total small RNAs from Oregon R	V083 male, one day	S29 male head #1	SRR001343 dcr-2 non-beta-eliminated	SRR001338 IR non-beta-eliminated	SRR001344 dcr-2 beta-eliminated	SRR001664 homozygous dcr-2_untreated	SRR001341 WT_males non-beta-eliminated	SRR001339 WT_females non-beta-eliminated	V084 female, one day	SRR001347 ago2 untreated	SRR001349 heterozygous dcr-2_untreated	S22 female head #1	SRR031704 2-O-methylated small RNAs from r2d2 homozygous flies	V082 embryo 14-24hr	S2 female head	S24 male body #2	GSM239041 fly heads, non beta-eliminated	SRR001348 ago2 oxidized	SRR001337 WT_females beta-eliminated	V008 S2-DRSC	S1 male head	SRR001346 ago2 beta-eliminated	SRR031698 2-O-methylated small RNAs from dcr-2 heterozygous flies	V002 IR+	GSM180328 adult heads (female heads, male heads)	SRR031700 2-O-methylated small RNAs from dcr-2 homozygous flies	V001 IR-	SRR031702 2-O-methylated small RNAs from r2d2 heterozygous flies	S27 0-1d Pupae (w)	GSM239052 S2 cells, non beta-eliminated	S23 female body #2	S9 0-1h #3 (7)	GSM280087 S2cell (AGO2IP)	S28 0-2d pupae	SRR031693_4	V076 ML-DmBG3-C2	S21 disk #2	SRR032092 mock oxidized	SRR001340 IR beta-eliminated	V098 dcr-2[L811fsX] ovary	S19 2-4day pupae #1	S5 imaginal disc	S4 female body	SRR014268 Embryo_0-2hrs rep1_HAR_0_2hr_Emb	V011 Sg4	SRR032094 ago2 knockdown	S3 male body	GSM379050 Armi Heterozygote	S18 3rd inster #2	S20 2-4day pupae#2	S10 2-6h #1 (8)	SRR014278 Ovary_rep1 w1118(fem)_x_Har(male)_F1	S32 s2+48 #2	SRR001342 WT_males beta-eliminated	GSM467729 WT	V081 embryo 2-6hr	GSM379057 Krimp Mutant	S35 KC+48 #2	GSM246084 D. melanogaster adult male heads 454	GSM379060 SpnE Heterozygote	S34 KC+48 #1	GSM239050 fly heads, beta-eliminated	GSM467730 r2d2	V009 CMEL1	GSM280084 loqs-/- ovaries (18-29nt)	V089 ago2[414] ovary total RNA	GSM280088 S2cell (AGO1IP)	S17 3rd inster #1	GSM379067 SpnE Mutant	S26 1st instar #2	GSM180335 imaginal discs	GSM180329 adult bodies (female bodies, male bodies)	V097 CS ovary	SRR014281 Ovary_rep1 wK(fem)_x_w1118(male)_F1	GSM343287 Drosophila Toll 10b mutant embryos	SRR014276 Ovary_rep1 NA(fem)_x_Har(male)_F1	GSM239051 S2 cells, beta-eliminated	V088 r2d2[1] ovary total RNA	V010 MLDmD20c5	GSM467731 loq	SRR029032 r2d2 knockdown	V033 CMEW1 Cl.8+ cell	GSM379065 Zuc Heterozygote	S13 6-10h #2 (11)	GSM180334 larvae: 1st instar and 3rd instars	S8 S2-48,+48, KC-48, +48 mix	V075 ML-DmBG1-C1	SRR029030 dcr-2 knockdown	GSM180333 late embryo (12-24)	V063 CS,ovary,AGO1IP	S7 12-24hr embryo	SRR014272 Embryo_0-2hrs rep1_wK_0_2hr_Emb	GSM379056 Krimp Heterozygote	GSM180336 pupae: 0-1 day, 0-2 day, 2-4 day	SRR023197 RNA Library from S2 control cells	SRR023402 total RNA extracted from NLS-P19 cells	GSM379054 Flam Heterozygote	V065 dcr-2[L811fsX], ovary, AGO1IP	SRR014273 Ovary_rep1_Har_P	GSM379064 Vasa Mutant	GSM379055 Flam Mutant	S25 1st instar #1	GSM379051 Armi Mutant	SRR014270 Embryo_0-2hrs rep1_NA_0_2hr_Emb	GSM379061 Squ Heterozygote	OSS6 Drosophila OSS cell small RNA libraries, rep2	GSM379059	V024 kc167 cell	GSM379058	GSM280086 WT ovaries (AGO2IP)	SRR014274 Ovary_rep1 LK(fem)_x_Har(male)_F1	S11 2-6h #2 (9)	V018 Kc167 cell	SRR014282 Ovary_rep1 wK_P	SRR014279 Ovary_rep1 w1118(fem)_x_wK(male)_F1	GSM180332 mid embryo (6-10)	S14 0-1hr #1 (A)	S16 KC -48 #1	OSS8 Drosophila OSS cell small RNA libraries, rep4	V019 GM2 cell	GSM154621 piRNAs associated with Ago3 from Drosophila melanogaster ovaries	SRR029031 loqs-ORF knockdown	S31 s2+48 #1	SRR010957 Aub IP in Ago3 trans-heterozygotes	SRR010952 Ago3 trans-heterozygotes, oxidized	SRR029033 lacZ knockdown	SRR010956 Piwi IP in Ago3 heterozygotes	GSM424740 S2 pKF63 stably transfected	SRR010954 Aub trans-heterozygotes, oxidized	SRR023400 total RNA extracted from P19 cells	GSM379063 Vasa Heterozygote	V020 S2R+ cell	SRR014269 Embryo_0-2hrs rep1_LK_0_2hr_Emb	SRR023407 RNA bound by NLS-P19 protein	GSM180337 tissue culture cells (S2 only)	SRR010960 wt, oxidized	V066 r2d2[1], ovary, AGO1IP	GSM379052 Aub Heterozygote	SRR014275 Ovary_rep1 LK_P	OSS2 Drosophila OSS cell small RNA libraries, rep1	GSM154622 piRNAs associated with Aubergine from Drosophila melanogaster ovaries	GSM154620 piRNAs associated with Piwi from Drosophila melanogaster ovaries	GSM154618 23-29 nucleotide RNAs from Drosophila melanogaster ovaries	S33 KC-48 #2	GSM231091 PIWI-associated piRNA in Drosophila melanogaster ovary (454 Pyrosequencing, 2006)	GSM379053 Aub Mutant	SRR032095 AGO1 IP dcr2 knockdown	SRR029029 dcr-1 knockdown	V028 CMEW1 Cl.8+ cell	SRR010959 Ago3 IP in heterozygotes	SRR014280 Ovary_rep1 w1118_P	V026 1182-4H cell	GSM180331 early embryo (2-6)	SRR014277 Ovary_rep1 NA_P	OSS7 Drosophila OSS cell small RNA libraries, rep3	GSM180330 very early embryo (0-1)	GSM424741 S2 pKF63 transiently transfected	SRR032096 AGO2 IP dcr2 knockdown	V021 ML-DmD21 cell	S15 S2 -48 #1	GSM266765 Siomi Lab fruit fly S2 AGO2 Cloned Sequences v1.0	S30 s2-48 #2	GSM379062 Squ Mutant	V025 S2R+ cell	SRR014271 Embryo_0-2hrs rep1_w1118_0_2hr_Emb	SRR010958 Piwi IP in Ago3 trans-heterozygotes	V067 S2-NP	GSM280082 WT ovaries (18-29nt)	SRR023399 RNA bound by P19 protein	SRR010955 Aub IP in Ago3 heterozygotes	GSM424739 S2 parental	GSM280083 dcr-2-/- ovaries (18-29nt)	SRR029028 untreated (mock)	SRR032093 ago1 knockdown	GSM280085 WT testes (18-24nt)	S12 6-10h #1 (10)	SRR010951 Ago3 heterozygotes, oxidized	GSM379066 Zuc Mutant	SRR010953 Aub heterozygotes, oxidized	V064 ago2[414], ovary, AGO1IP
.................GTAGTGTTGTCCACAATAGAC...........................................................................................................	21	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
...................AGTGTTGTCCACAATAGAC...........................................................................................................	19	1	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTTGG.....................................................................................	22	1	47	2	0	1	0	1	0	3	1	1	3	0	0	3	0	0	0	0	1	0	1	0	16	0	0	0	1	0	0	0	0	0	2	0	0	2	0	6	2	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTTG......................................................................................	21	1	11	1	1	1	0	4	0	0	1	1	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTTGGTGT..................................................................................	25	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTT.......................................................................................	20	1	2	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTTGGT....................................................................................	23	1	248	3	8	12	22	19	6	9	12	14	21	9	4	0	0	1	2	2	11	2	0	4	18	33	1	0	0	0	1	0	0	0	3	0	0	0	2	15	0	0	0	0	0	0	7	0	0	0	0	0	2	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................CTTAGTTTTCGACGTGTTTTGGTG...................................................................................	24	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.......................................TTAGTTTTCGACGTGTTTTGGT....................................................................................	22	1	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
..........................................GTTTTCGACGTGTTTTGGT....................................................................................	19	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
..................................................CGTGTTTTGGTGTGCTGGGGA..........................................................................	21	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.............................................................GTGCTGGGGAGTTCTATTCCG...............................................................	21	1	3	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.............................................................GTGCTGGGGAGTTCTATTCCGAT.............................................................	23	1	8	0	0	0	0	2	0	0	2	0	0	0	0	0	2	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
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...................................................................................TTGAAACCGTCCAAAACTGAGG........................................	22	1	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
...................................................................................TTGAAACCGTCCAAAACTGAGGC.......................................	23	1	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGAGGCCA.....................................	24	1	3	0	0	0	0	1	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGAGGC.......................................	22	1	48826	7548	6263	3966	3182	2565	2374	1875	1995	1896	2344	2274	1601	1322	1420	795	762	762	1050	788	740	294	468	349	211	175	190	120	121	82	114	110	64	124	64	39	98	35	73	46	34	35	22	48	18	12	32	14	14	15	22	25	13	16	13	4	8	16	14	12	8	11	1	3	2	7	8	6	5	9	2	5	5	5	3	3	2	5	4	5	5	1	1	4	0	4	0	1	2	0	3	2	2	0	0	1	1	0	1	1	1	0	0	0	0	1	1	1	0	1	0	1	1	1	1	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGAGG........................................	21	1	42500	5559	2862	3927	3435	3186	2600	2713	2196	1803	1581	1157	1343	1447	769	1025	919	919	744	824	806	764	386	23	160	134	103	123	94	135	94	68	58	7	57	55	9	28	5	28	40	32	35	6	14	30	5	22	18	14	5	4	11	5	5	14	9	0	1	3	5	3	12	5	0	4	2	4	3	1	6	3	0	1	2	2	4	1	1	0	0	3	3	0	1	0	1	2	1	1	0	1	0	1	2	1	0	2	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGAG.........................................	20	1	3641	556	102	210	338	377	226	309	168	156	50	151	142	153	41	105	106	106	19	63	82	37	20	1	20	4	8	8	10	7	9	3	3	0	2	6	0	3	1	4	4	2	1	2	1	0	0	0	1	2	0	0	1	0	1	0	1	0	0	0	2	0	0	4	3	0	0	0	2	0	1	0	1	0	0	1	0	0	0	0	0	1	0	0	2	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGA..........................................	19	1	352	40	3	10	40	54	16	48	26	9	1	5	3	15	2	18	4	4	1	6	15	4	12	0	0	0	0	1	0	0	0	0	1	0	0	6	0	1	0	1	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
....................................................................................TGAAACCGTCCAAAACTGAGGCC......................................	23	1	108	17	8	6	4	7	5	1	4	7	3	11	2	4	0	2	1	1	1	3	3	4	2	0	0	2	3	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
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.....................................................................................GAAACCGTCCAAAACTGAGGC.......................................	21	1	1616	322	226	5	257	144	48	98	54	86	2	9	57	51	56	43	30	30	2	37	30	0	9	1	0	0	0	9	3	0	0	3	1	0	0	0	0	1	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.....................................................................................GAAACCGTCCAAAACTGAGGCC......................................	22	1	3	0	0	0	2	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
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......................................................................................AAACCGTCCAAAACTGAGG........................................	19	1	45	7	3	0	6	5	8	2	7	1	1	0	1	2	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................................................................AAACCGTCCAAAACTGAGGC.......................................	20	1	67	11	8	1	10	9	3	4	6	4	1	0	2	2	1	0	2	2	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.......................................................................................AACCGTCCAAAACTGAGGC.......................................	19	1	8	4	0	0	0	2	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
.......................................................................................AACCGTCCAAAACTGAGG........................................	18	1	7	1	0	0	0	1	1	0	1	2	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
........................................................................................ACCGTCCAAAACTGAGGC.......................................	18	1	9	4	0	0	0	0	2	0	1	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
..........................................................................................................CAACTGTGAGGCGCGAGCATC..................	21	1	1	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

Antisense strand

	Size	Blast	Total	SRR031696_2152	SRR001345 ago2 non-beta-eliminated	V090 CS  male total RNA	SRR031703 Total small RNAs from r2d2 homozygous flies	SRR029633 total small RNAs from hen1 homozygous flies	SRR031699 Total small RNAs from dcr-2 homozygous flies	SRR031701 Total small RNAs from r2d2 heterozygous flies	SRR031697 Total small RNAs from dcr-2 heterozygous flies	SRR031692 Total small RNAs from Oregon R	V083 male, one day	S29 male head #1	SRR001343 dcr-2 non-beta-eliminated	SRR001338 IR non-beta-eliminated	SRR001344 dcr-2 beta-eliminated	SRR001664 homozygous dcr-2_untreated	SRR001341 WT_males non-beta-eliminated	SRR001339 WT_females non-beta-eliminated	V084 female, one day	SRR001347 ago2 untreated	SRR001349 heterozygous dcr-2_untreated	S22 female head #1	SRR031704 2-O-methylated small RNAs from r2d2 homozygous flies	V082 embryo 14-24hr	S2 female head	S24 male body #2	GSM239041 fly heads, non beta-eliminated	SRR001348 ago2 oxidized	SRR001337 WT_females beta-eliminated	V008 S2-DRSC	S1 male head	SRR001346 ago2 beta-eliminated	SRR031698 2-O-methylated small RNAs from dcr-2 heterozygous flies	V002 IR+	GSM180328 adult heads (female heads, male heads)	SRR031700 2-O-methylated small RNAs from dcr-2 homozygous flies	V001 IR-	SRR031702 2-O-methylated small RNAs from r2d2 heterozygous flies	S27 0-1d Pupae (w)	GSM239052 S2 cells, non beta-eliminated	S23 female body #2	S9 0-1h #3 (7)	GSM280087 S2cell (AGO2IP)	S28 0-2d pupae	SRR031693_4	V076 ML-DmBG3-C2	S21 disk #2	SRR032092 mock oxidized	SRR001340 IR beta-eliminated	V098 dcr-2[L811fsX] ovary	S19 2-4day pupae #1	S5 imaginal disc	S4 female body	SRR014268 Embryo_0-2hrs rep1_HAR_0_2hr_Emb	V011 Sg4	SRR032094 ago2 knockdown	S3 male body	GSM379050 Armi Heterozygote	S18 3rd inster #2	S20 2-4day pupae#2	S10 2-6h #1 (8)	SRR014278 Ovary_rep1 w1118(fem)_x_Har(male)_F1	S32 s2+48 #2	SRR001342 WT_males beta-eliminated	GSM467729 WT	V081 embryo 2-6hr	GSM379057 Krimp Mutant	S35 KC+48 #2	GSM246084 D. melanogaster adult male heads 454	GSM379060 SpnE Heterozygote	S34 KC+48 #1	GSM239050 fly heads, beta-eliminated	GSM467730 r2d2	V009 CMEL1	GSM280084 loqs-/- ovaries (18-29nt)	V089 ago2[414] ovary total RNA	GSM280088 S2cell (AGO1IP)	S17 3rd inster #1	GSM379067 SpnE Mutant	S26 1st instar #2	GSM180335 imaginal discs	GSM180329 adult bodies (female bodies, male bodies)	V097 CS ovary	SRR014281 Ovary_rep1 wK(fem)_x_w1118(male)_F1	GSM343287 Drosophila Toll 10b mutant embryos	SRR014276 Ovary_rep1 NA(fem)_x_Har(male)_F1	GSM239051 S2 cells, beta-eliminated	V088 r2d2[1] ovary total RNA	V010 MLDmD20c5	GSM467731 loq	SRR029032 r2d2 knockdown	V033 CMEW1 Cl.8+ cell	GSM379065 Zuc Heterozygote	S13 6-10h #2 (11)	GSM180334 larvae: 1st instar and 3rd instars	S8 S2-48,+48, KC-48, +48 mix	V075 ML-DmBG1-C1	SRR029030 dcr-2 knockdown	GSM180333 late embryo (12-24)	V063 CS,ovary,AGO1IP	S7 12-24hr embryo	SRR014272 Embryo_0-2hrs rep1_wK_0_2hr_Emb	GSM379056 Krimp Heterozygote	GSM180336 pupae: 0-1 day, 0-2 day, 2-4 day	SRR023197 RNA Library from S2 control cells	SRR023402 total RNA extracted from NLS-P19 cells	GSM379054 Flam Heterozygote	V065 dcr-2[L811fsX], ovary, AGO1IP	SRR014273 Ovary_rep1_Har_P	GSM379064 Vasa Mutant	GSM379055 Flam Mutant	S25 1st instar #1	GSM379051 Armi Mutant	SRR014270 Embryo_0-2hrs rep1_NA_0_2hr_Emb	GSM379061 Squ Heterozygote	OSS6 Drosophila OSS cell small RNA libraries, rep2	GSM379059	V024 kc167 cell	GSM379058	GSM280086 WT ovaries (AGO2IP)	SRR014274 Ovary_rep1 LK(fem)_x_Har(male)_F1	S11 2-6h #2 (9)	V018 Kc167 cell	SRR014282 Ovary_rep1 wK_P	SRR014279 Ovary_rep1 w1118(fem)_x_wK(male)_F1	GSM180332 mid embryo (6-10)	S14 0-1hr #1 (A)	S16 KC -48 #1	OSS8 Drosophila OSS cell small RNA libraries, rep4	V019 GM2 cell	GSM154621 piRNAs associated with Ago3 from Drosophila melanogaster ovaries	SRR029031 loqs-ORF knockdown	S31 s2+48 #1	SRR010957 Aub IP in Ago3 trans-heterozygotes	SRR010952 Ago3 trans-heterozygotes, oxidized	SRR029033 lacZ knockdown	SRR010956 Piwi IP in Ago3 heterozygotes	GSM424740 S2 pKF63 stably transfected	SRR010954 Aub trans-heterozygotes, oxidized	SRR023400 total RNA extracted from P19 cells	GSM379063 Vasa Heterozygote	V020 S2R+ cell	SRR014269 Embryo_0-2hrs rep1_LK_0_2hr_Emb	SRR023407 RNA bound by NLS-P19 protein	GSM180337 tissue culture cells (S2 only)	SRR010960 wt, oxidized	V066 r2d2[1], ovary, AGO1IP	GSM379052 Aub Heterozygote	SRR014275 Ovary_rep1 LK_P	OSS2 Drosophila OSS cell small RNA libraries, rep1	GSM154622 piRNAs associated with Aubergine from Drosophila melanogaster ovaries	GSM154620 piRNAs associated with Piwi from Drosophila melanogaster ovaries	GSM154618 23-29 nucleotide RNAs from Drosophila melanogaster ovaries	S33 KC-48 #2	GSM231091 PIWI-associated piRNA in Drosophila melanogaster ovary (454 Pyrosequencing, 2006)	GSM379053 Aub Mutant	SRR032095 AGO1 IP dcr2 knockdown	SRR029029 dcr-1 knockdown	V028 CMEW1 Cl.8+ cell	SRR010959 Ago3 IP in heterozygotes	SRR014280 Ovary_rep1 w1118_P	V026 1182-4H cell	GSM180331 early embryo (2-6)	SRR014277 Ovary_rep1 NA_P	OSS7 Drosophila OSS cell small RNA libraries, rep3	GSM180330 very early embryo (0-1)	GSM424741 S2 pKF63 transiently transfected	SRR032096 AGO2 IP dcr2 knockdown	V021 ML-DmD21 cell	S15 S2 -48 #1	GSM266765 Siomi Lab fruit fly S2 AGO2 Cloned Sequences v1.0	S30 s2-48 #2	GSM379062 Squ Mutant	V025 S2R+ cell	SRR014271 Embryo_0-2hrs rep1_w1118_0_2hr_Emb	SRR010958 Piwi IP in Ago3 trans-heterozygotes	V067 S2-NP	GSM280082 WT ovaries (18-29nt)	SRR023399 RNA bound by P19 protein	SRR010955 Aub IP in Ago3 heterozygotes	GSM424739 S2 parental	GSM280083 dcr-2-/- ovaries (18-29nt)	SRR029028 untreated (mock)	SRR032093 ago1 knockdown	GSM280085 WT testes (18-24nt)	S12 6-10h #1 (10)	SRR010951 Ago3 heterozygotes, oxidized	GSM379066 Zuc Mutant	SRR010953 Aub heterozygotes, oxidized	V064 ago2[414], ovary, AGO1IP
........................................................................TTCTATTCCGATTGAAACCGTCCAAA...............................................	26	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
..................................................................................................................AGGCGCGAGCATCTATCCA............	19	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
......................................................................................................................GCGAGCATCTATCCAAAAAGC......	21	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0